31. Leiomyosarcoma

Staining: HE

Overview

Organ: Unknown

Description: The whole slide is just tumor, except in the upper right corner where there is some fat tissue, which is infiltrated by the tumor, indicating that it isn’t benign. There is coagulative necrosis, severe atypia and many mitotic figures. The tumor cells are spindle shaped with “cigar”-shaped nuclei.

Tumour infiltrates the fat tissue

Diagnosis: Leimyosarcoma

Causes: Nothing special

Theory: The presence of coagulative necrosis, severe atypia and many mitotic figures indicates that this is a malignant tumor and not a benign one.

Coagulation necrosis

Cigar-shaped nuclei and mitotic figures

I don’t think this atypia looks severe but apparently it is