24. Prion disease, spongioform encephalopathy
Staining: HE
Organ: Brain
Description:
There is a small region of the grey matter where there are “holes” between neurons. Some vessels resemble these holes.
Diagnosis: Prion disease
Causes:
- Infection by prions
Theory:
As prions accumulate inside the neurons will the neurons commit apoptosis, which leaves behind small holes between the healthy cells.
