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• 17:45, 23 April 2023 Nikolas talk contribs created page 69. Nitroimidazoles. RNA polymerase inhibitors (Created page with "''RNA polymerase inhibitors include the macrocyclines and rifamycins''. == Nitroimidazoles == === Compounds === * Metronidazole * Tinidazole The most important nitroimidazole is metronidazole, but tinidazole is very similar. === Mechanism of action === Nitroimidazoles are prodrugs which are metabolized into reactive metabolites by enzymes inside the pathogen cell. The reactive metabolites then bind to and damage DNA and proteins. This effect is bactericidal. === Me...") Tag: Visual edit