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- 14:21, 10 March 2023 Nikolas talk contribs created page 52. Disorders of nucleic acid metabolism. Gout (Created page with "The metabolism of nucleic acid involves breaking them down into pyrimidines or purines. The metabolism of purines (like AMP, IMP and GMP) is the most clinically important. thumb|321x321px|Breakdown of purines Breakdown of purines involves breaking them down to uric acid (or urate) with the enzyme ''xanthine oxidase''. Uric acid is poorly water soluble and is therefore prone to crystallize. Normal plasma level of uric acid is 6.4 mg/dL. T...") Tag: Visual edit