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• 09:50, 31 January 2023 Nikolas talk contribs created page 37. Allergic reaction (Created page with "''Main article: Allergy'' == Mast cells == The main mediators of allergic reactions are the mast cells, but basophils are also involved. They are activated when <abbr>IgE</abbr> bound to their surface FcεRI and this IgE subsequently binds to an antigen. This causes the activation of two protein tyrosine kinases in the cell, Lyn and Syk, which transmit the signal into the cell, causing the mast cell to release the molecules that mediates the allergic reaction. The mole...") Tag: Visual edit