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- 21:42, 3 November 2022 Nikolas talk contribs created page 23. Senile plaques and neurofibrillar degeneration (Created page with "'''Staining''': Silver stain (Bielschowsky) '''Organ''': Brain, hippocampus '''Description''': The hippocampus is visible and that’s where the characteristic findings are visible on this slide. ''Senile plaques'' are extracellular deposits of β-amyloid that are surrounded by silver-positive proteins. The amyloids themselves aren’t stained by silver and are therefore pale. These plaques are therefore visible as large black foci with a pale core. ''Neurofibrillar...") Tag: Visual edit