59. Paget’s disease
Organ: Breast
Description:
The nipple is firm, inflamed and hyperkeratotic.
Diagnosis: Paget disease of the breast
Causes:
- DCIS or invasive carcinoma
Theory:
Paget disease of the breast is a manifestation of DCIS or invasive breast carcinoma where the nipple becomes inflamed and hyperkeratotic as tumor cells invade the skin of the nipple.