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Cutaneous T-cell lymphomas

Revision as of 08:47, 21 July 2024 by Nikolas (talk | contribs) (Created page with "<section begin="dermatology" /> * Mycosis fungoides ** <abbr>CD4</abbr>+ T-cell lymphoma ** Progresses slowly ** Stage I – patch stage *** Scaly, pruritic, well-demarcated patches ** Stage II – plaque stage *** Scaly, pruritic, well-demarcated plaques *** Large ** Stage III – tumor stage *** Dome-shaped purple or red nodules ** Treatment *** Topical steroids *** Topical chemo *** Phototherapy *** Biological therapy *** Systemic chemo * Sézary syndrome ** Can devel...")
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  • Mycosis fungoides
    • CD4+ T-cell lymphoma
    • Progresses slowly
    • Stage I – patch stage
      • Scaly, pruritic, well-demarcated patches
    • Stage II – plaque stage
      • Scaly, pruritic, well-demarcated plaques
      • Large
    • Stage III – tumor stage
      • Dome-shaped purple or red nodules
    • Treatment
      • Topical steroids
      • Topical chemo
      • Phototherapy
      • Biological therapy
      • Systemic chemo
  • Sézary syndrome
    • Can develop from mycosis fungoides or de novo
    • Clinical triad
      • Systemic skin lesions
        • Erythroderma
        • Palmar and plantar hyperkeratosis
        • Pruritus
      • Generalized lymphadenopathy
      • Atypical T-cells in blood
    • Treatment
      • Extracorporal photopheresis
      • Phototherapy
      • Chemotherapy
  • Adult cutaneous T-cell leukaemia/lymphoma
    • HTLV-I associated
    • Similar lesions to mycosis fungoides