Lyme disease

• Tick-borne
• Borrelia burgdorferi
• Clinical features
  • Stage I – early localized Lyme disease
    • Within 7 – 14 days
    • Erythema migrans
      • Circular, slowly-expanding red ring with central clearing around the bite site
      • Target-like rash
    • Flu-like symptoms
  • Stage II – early disseminated Lyme disease
    • Multiple erythema migrans
    • Migratory arthralgia
    • Early neuroborreliosis
    • Lyme carditis
  • Stage III – late Lyme disease
    • Acrodermatitis chronica atrophicans
      • Inflammation and atrophy of skin of extremities
    • Chronic Lyme arthritis
    • Late neuroborreliosis
• Diagnosis
  • Clinical diagnosis based on symptoms
  • Serology can be used to confirm
• Treatment
  • Doxycycline
    • First-line
  • Amoxicillin
    • In pregnant
  • Ceftriaxone
    • If neuroborreliosis or Lyme carditis