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Cryoglobulinaemic vasculitis

Revision as of 17:36, 17 July 2024 by Nikolas (talk | contribs) (Created page with "<section begin="dermatology" />* Cryoglobulins = immunoglobulins that precipitate in the cold ** They precipitate within the walls of small vessels * Etiology ** Viral infections ** Autoimmune connective tissue diseases ** Haematological malignancies * Clinical features ** Palpable purpura (in 90%) ** Myalgia ** Arthralgia ** Peripheral neuropathy ** Glomerulonephritis * Diagnosis ** Examination of cryoglobulins in blood during attack * Treatment ** Treat underlying dise...")
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  • Cryoglobulins = immunoglobulins that precipitate in the cold
    • They precipitate within the walls of small vessels
  • Etiology
    • Viral infections
    • Autoimmune connective tissue diseases
    • Haematological malignancies
  • Clinical features
    • Palpable purpura (in 90%)
    • Myalgia
    • Arthralgia
    • Peripheral neuropathy
    • Glomerulonephritis
  • Diagnosis
    • Examination of cryoglobulins in blood during attack
  • Treatment
    • Treat underlying disease
    • If severe
      • Steroids
      • Immunosuppressants
      • Biological therapy