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Dermatitis herpetiformis

Revision as of 17:52, 17 July 2024 by Nikolas (talk | contribs) (Created page with "<section begin="dermatology" />* In young adults * Risk factors ** Coeliac disease ** Iodide sensitivity ** HLA-DR3 ** HLA-DQ2 * Pathomechanism ** Tissue transglutaminase and epidermal transglutaminase antibodies * Clinical features ** Chronic, recurrent ** Tense, grouped, subepidermal vesicles *** Herpetiform appearance, hence the name ** Intensely pruritic ** Bilateral, symmetrical distribution *** Elbows, knees ** No mucosal involvement * Diagnosis ** Coeliac antibodi...")
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  • In young adults
  • Risk factors
    • Coeliac disease
    • Iodide sensitivity
    • HLA-DR3
    • HLA-DQ2
  • Pathomechanism
    • Tissue transglutaminase and epidermal transglutaminase antibodies
  • Clinical features
    • Chronic, recurrent
    • Tense, grouped, subepidermal vesicles
      • Herpetiform appearance, hence the name
    • Intensely pruritic
    • Bilateral, symmetrical distribution
      • Elbows, knees
    • No mucosal involvement
  • Diagnosis
    • Coeliac antibodies
    • Histology and immunofluorescence
  • Treatment
    • Dapsone
    • Gluten-free diet