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Human papilloma virus infection

Revision as of 20:08, 15 July 2024 by Nikolas (talk | contribs) (Created page with "{{:Stub}} <section begin="dermatology" />* Warts (verruca) ** Histology *** Hyperkeratosis (hyperplasia of str. corneum) *** Acanthosis (hyperplasia of epidermis) *** Papillomatosis ** Hard papules/plaques ** Risk factors *** Immunosuppression ** Due to HPV ** Verruca vulgaris (common wart) *** HPV 1, 2, 4, 7 *** Most common in kids *** On elbows, knees, fingers, palms *** Skin-coloured or whitish, rough, scaly papules *** Cauliflower-appearance ** Verruca plana (flat w...")
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  • Warts (verruca)
    • Histology
      • Hyperkeratosis (hyperplasia of str. corneum)
      • Acanthosis (hyperplasia of epidermis)
      • Papillomatosis
    • Hard papules/plaques
    • Risk factors
      • Immunosuppression
    • Due to HPV
    • Verruca vulgaris (common wart)
      • HPV 1, 2, 4, 7
      • Most common in kids
      • On elbows, knees, fingers, palms
      • Skin-coloured or whitish, rough, scaly papules
      • Cauliflower-appearance
    • Verruca plana (flat warts)
      • HPV 3, 11
      • On face, back of hand, legs
      • Skin-coloured, smooth papules, flat surface
    • Verruca plantaris (plantar warts)
      • HPV 1, 2, 4
      • Soles of the feet
      • Skin-coloured
      • Rough surface
    • Treatment
      • Usually resolves by themselves (can take years)
      • Topical treatment
        • Keratolytics
          • Salicylic acid
        • Retinoic acid
        • Cytostatic
          • Podophyllin
          • 5-FU cream
        • Immune therapy
          • Imiquimod
      • Surgery
        • Cryotherapy
        • Surgical excision
          • Leaves permanent, painful scars
      • Prevention
        • Vaccination
          • Cervarix – 16, 18
          • Silgard – 6, 11, 16, 18
          • Gardasil 9 – 6, 11, 16, 18, 31, 33, 45, 52, 58
  • Condyloma acuminata – genital warts
    • HPV 6, 11
    • Exophytic, cauliflower-like lesions
    • In anogenital area or mucous membranes
    • STD
  • Giant condyloma acuminatum
    • HPV 6, 11
    • Exophytic wart-like locally invasive squamous cell carcinoma without tendency to metastasize
  • Precancerous lesions
    • Vulvar intraepithelial neoplasia
    • Vaginal intraepithelial neoplasia
    • Flat condylomata
      • Flat, white-brown plaques in anogenital region
      • High risk of malignancy
  • Anogenital squamous cell carcinoma
    • Vaginal cancer
    • Vulvar cancer
    • Anal cancer
    • Penile cancer