Polyclonal gammopathy

Polyclonal gammopathy refers to any condition where there is excessive amounts of polyclonal gammaglobulin in the blood, as evidenced by a wide (but not peaked) gamma band on serum electrophoresis. Polyclonal gammopathy is the opposite of monoclonal gammopathy.

Polyclonal gammopathy is a part of the regular immunologial response to any infection and many forms of inflammation, where B cells produce antibodies (immunoglobulins).