Calcium

Revision as of 21:23, 21 March 2024 by Nikolas (talk | contribs) (Created page with "{{:Stub}}<section begin="clinical biochemistry" /> '''Calcium''' is an ion in the body. * Roles ** Comprises bone ** 1 kg in adults *** 99% in bone ** Muscle contraction ** Neurotransmission ** Membrane transport ** Enzymes ** Coagulation * 45% free * 45% protein bound * 10% anion bound * Regulation ** Kidney ** PTH *** Decreased calcium stimulates PTH *** Increased phosphate stimulates PTH *** Increases Ca2+ reabsorption in tubule *** Increases phosphate excretion in...")

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

This article is a stub, meaning that it is unfinished. It will eventually be expanded.

Calcium is an ion in the body.

Roles
- Comprises bone
- 1 kg in adults
  - 99% in bone
- Muscle contraction
- Neurotransmission
- Membrane transport
- Enzymes
- Coagulation
45% free
45% protein bound
10% anion bound
Regulation
- Kidney
- PTH
  - Decreased calcium stimulates PTH
  - Increased phosphate stimulates PTH
  - Increases Ca2+ reabsorption in tubule
  - Increases phosphate excretion in tubule
  - Increases vitamin D production
  - Increases bone resorption
- Vitamin D
  - Increases Ca2+ reabsorption in tubule
  - Increases Ca2+ reabsorption in GI tract
  - Decrease phosphate excretion in tubule
  - Increase bone mineralization
- (Calcitonin)
  - Opposite of PTH
  - Tumor marker