Pernicious anaemia

Revision as of 17:09, 19 October 2023 by Nikolas (talk | contribs) (Created page with "'''Pernicious anaemia''' is an autoimmune disease where autoantibodies are produced against intrinsic factor or the parietal cells which produce IF. These antibodies will either destroy the parietal cells or block vitamin B12 from binding to IF, both of which result in B12 malabsorption, causing B12 deficiency and megaloblastic anaemia. Category:Haematology")

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Pernicious anaemia is an autoimmune disease where autoantibodies are produced against intrinsic factor or the parietal cells which produce IF. These antibodies will either destroy the parietal cells or block vitamin B12 from binding to IF, both of which result in B12 malabsorption, causing B12 deficiency and megaloblastic anaemia.