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Hepatitis D

Revision as of 20:14, 18 August 2023 by Nikolas (Sọ̀rọ̀ | contribs) (Created page with "The hepatitis D virus is defective, as it lacks certain parts to function. Because of this, it can only cause infection when hepatitis B is also present, as the hepatitis D virus requires the hepatitis B surface antigen (HBsAg) for it to function. Like hepatitis B and C, transmission is parenteral, sexual, or perinatal. == Clinical features == Coinfection with HBV causes more severe acute hepatitis or fulminant hepatitis, but no increased risk of chronic hepatitis. Su...")
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The hepatitis D virus is defective, as it lacks certain parts to function. Because of this, it can only cause infection when hepatitis B is also present, as the hepatitis D virus requires the hepatitis B surface antigen (HBsAg) for it to function.

Like hepatitis B and C, transmission is parenteral, sexual, or perinatal.

Clinical features

Coinfection with HBV causes more severe acute hepatitis or fulminant hepatitis, but no increased risk of chronic hepatitis.

Superinfection of a person with chronic HBV increases risk of cirrhosis and accelerates disease progression.

Diagnosis and evaluation

Diagnosis is based on serology. IgM anti-HDV indicates acute infection, while IgG anti-HDV indicates chronic infection.