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File:RANK-RANKL-mediated osteoclastogenesis.jpg

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RANK-RANKL-mediated_osteoclastogenesis.jpg ‎(500 × 268 pixels, file size: 19 KB, MIME type: image/jpeg)

This figure shows how inflammatory cytokines (TNFα and IL-1) increase production of RANKL, which binds to RANK on osteoclast precursors and activate them. From https://royalsocietypublishing.org/doi/10.1098/rsob.160230?width=800&height=600&carousel=1

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