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14. History and objectives of epidemiology
- Epidemiology is the study of determinants and distribution of disease
- Clinical epidemiology is the use of epidemiology to improve prevention, detection, and treatment of disease
- History of epidemiology
- Hippocrates: “Quality of water, how people live, what they drink and eat, whether they exercise, affect their health”
- Ignaz Semmelweis discovered that hand disinfection reduced the incidence of puerperal fever
- John Snow
- The father of epidemiology
- Challenged the “miasma theory”, which described that disease occurs due to “miasma”, an airborne poison from unsanitary conditions
- Snow’s hypothesis was that a part of London had increased incidence of cholera due to that part of London receiving water from a polluted part of the river Thames
- He also traced a cholera outbreak to a single water pump which was contaminated by a young cholera patient
- James Lind: divided sailors with scurvy into groups, and gave citrus fruits to some of them
- Sir Percival Pott:
- Recognized the association between scrotal cancer and chimney sweeping
- Katsusaburou Yamagiwa: Confirmed that coal tar could induce cancer by inducing cancer in rabbit ears
- Eradication of smallpox in 1978
- Identification of AIDS, prediction that it was due to a sexually transmitted virus and development of preventative measures before the HIV virus itself was identified
- Infants who lie on their stomach have much higher risk of SIDS
- Objectives of epidemiology
- Description of diseases occurrences and patterns
- Identification of causative agents and risk factors
- Application of results at the population level