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  • 14:09, 22 November 2022 Nikolas talk contribs created page 18. Molecular basics of carcinogenesis (Created page with "* DNA damage to normal cell -> mutations in genome -> altered gene product -> Tumor suppressors ↓ or oncogenes ↑ * Protective mechanisms against carcinogenesis ** DNA repair enzymes ** Tumor suppressors * Characteristics of cancer cells ** Inhibition of apoptosis + lack of response to inhibitory factors -> capable of self-maintained replication, long survival ** Mutagenic agents/defective DNA repair -> genetic instability -> more mutations ** Capable of angiogenesis...") Tag: Visual edit