44. NRDS

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Revision as of 19:17, 19 May 2022 by Nikolas (talk | contribs) (Created page with "'''Staining''': PAS '''Organ''': Lung '''Description''': The lung parenchyme look odd, and there are much fewer (open) alveoli than normal. The alveoli that are present are covered by a hyaline “membrane”. '''Diagnosis''': Neonatal respiratory distress syndrome '''Causes''': * Lack of pulmonary surfactant '''Theory''': In NRDS are most alveoli atelectic (collapsed), which is why so few alveoli are visible and why the lung parenchyme looks “denser”. The at...")
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Staining: PAS

Organ: Lung

Description:

The lung parenchyme look odd, and there are much fewer (open) alveoli than normal. The alveoli that are present are covered by a hyaline “membrane”.

Diagnosis: Neonatal respiratory distress syndrome

Causes:

  • Lack of pulmonary surfactant

Theory:

In NRDS are most alveoli atelectic (collapsed), which is why so few alveoli are visible and why the lung parenchyme looks “denser”. The atelectasis damages the alveolo-capillary membrane, increasing the permeability of it, which allows fibrous exudate to enter the alveoli. It is this exudate that forms the hyaline membranes.

RBCs enter the alveoli when the alveolo-capillary membrane is damaged.

Overview of the slide
The area between the open alveoli contains many atelectic alveoli
Hyaline membrane covering the wall of the alveolus