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- 10:02, 6 May 2022 Nikolas talk contribs created page 19. Definition, types and organ examples of hyperplasia (Created page with "Hyperplasia is an increase of the number of cells in an organ or tissue by cell division, resulting in an increase in the mass of the organ. There are different types of hyperplasia: == Physiological hyperplasia == There are two types of physiological hyperplasia, hormonal and compensatory. * Hormonal hyperplasia ** This is the increase of functional capacity of an organ when its needed. ** An example is when a woman is ''pregante'' and the glandular epithelium of the...") Tag: Visual edit
- 09:53, 6 May 2022 Nikolas talk contribs created page 18. Causes of atrophy; general gross morphology and microscopical characteristics. Pathomechanism of atrophy. Hypoplasia, aplasia, agenesia. Osteoporosis. (Created page with "''Written by ms. Worldwide, edited by Nikolas'' == Hypoplasia == Incomplete development or underdevelopment of an organ or tissue. == Aplasia == Aplasia refers to defective development of an organ or tissue beyond an early embryonic stage. As a result, the embryonic remnants of the organ are often present. == Agenesia == Agenesis refers to complete loss of an organ or part due to development never beginning in the embryonic stage. == Atrophy == Atrophy means that an...") Tag: Visual edit
- 09:53, 6 May 2022 Nikolas talk contribs created page File:Osteoporosis.png
- 09:53, 6 May 2022 Nikolas talk contribs uploaded File:Osteoporosis.png
- 09:53, 6 May 2022 Nikolas talk contribs created page File:Brown atrophy of the heart.png
- 09:53, 6 May 2022 Nikolas talk contribs uploaded File:Brown atrophy of the heart.png
- 09:47, 6 May 2022 Nikolas talk contribs created page 17. Pathology of obesity and diabetes (Created page with "== Obesity == === Introduction and definition === Overweight and obesity are states of increased body weight due to adipose tissue accumulation that can contribute to bad health effects. Obesity (and to a lesser extent overweight) is a chronic disease which leads to significant excess morbidity and mortality. It’s also an epidemic that is rising for every year, and is associated with many diseases, including diabetes, hypertension and physical inactivity. The Body Ma...") Tag: Visual edit
- 09:46, 6 May 2022 Nikolas talk contribs created page File:Complications of diabetes.png
- 09:46, 6 May 2022 Nikolas talk contribs uploaded File:Complications of diabetes.png
- 09:45, 6 May 2022 Nikolas talk contribs created page File:BMI scale.png
- 09:45, 6 May 2022 Nikolas talk contribs uploaded File:BMI scale.png
- 09:44, 6 May 2022 Nikolas talk contribs created page 16. General characterisation of amyloidosis. Physico-chemical, ultrastructural and histochemical nature of amyloid. Types of amyloid (Created page with "Amyloidosis is a disorder of protein misfolding. It results in protein fibrils called amyloids depositing in interstitial space (not inside cells) and cause damage there. The protein fibrils come from proteins that are misfolded, however the specific protein that is misfolded can vary. We know of at least 23 different proteins that can aggregate to form amyloid fibrils. The reason these proteins aggregate is because when they’re misfolded they expose more β-sheets. T...") Tag: Visual edit
- 09:43, 6 May 2022 Nikolas talk contribs created page File:Amyloid deposition between myocardial fibres..png
- 09:43, 6 May 2022 Nikolas talk contribs uploaded File:Amyloid deposition between myocardial fibres..png
- 09:43, 6 May 2022 Nikolas talk contribs created page File:Amyloid deposition in a Langerhans islet..png
- 09:43, 6 May 2022 Nikolas talk contribs uploaded File:Amyloid deposition in a Langerhans islet..png
- 09:42, 6 May 2022 Nikolas talk contribs created page File:Amyloid deposition in the glomeruli.png
- 09:42, 6 May 2022 Nikolas talk contribs uploaded File:Amyloid deposition in the glomeruli.png
- 09:41, 6 May 2022 Nikolas talk contribs created page 15. Pathomechanism and clinicopathological forms of stone formation (Created page with "== Cholelithiasis == The presence of gallstones in the gallbladder is called cholelithiasis. It affects 20% of adults in western countries. We distinguish two main types of gallstones: cholesterol stones, which are made up of crystalline cholesterol and accounts for 80% of stones found in the west, and pigment stones, made up of bilirubin calcium salts. The presence of stones in the common bile duct is called choledocholithiasis. Cholesterol stones are always formed in...") Tag: Visual edit
- 09:32, 6 May 2022 Nikolas talk contribs created page 14. Dystrophic and metastatic calcification. Organ manifestations (Created page with "Calcification is the pathological deposition of calcium in tissues. We distinguish two different types: dystrophic calcification and metastatic calcification. = Dystrophic calcification = Dystrophic calcification occurs in necrotic, injured or even dead tissues. It occurs with normal calcium level in the blood, meaning that hypercalcaemia is not a prerequisite for this type of calcification. It begins with an initiation, which is when a calcium “core” is formed. La...") Tag: Visual edit
- 09:32, 6 May 2022 Nikolas talk contribs created page File:Nephrocalcinosis x-ray.png
- 09:32, 6 May 2022 Nikolas talk contribs uploaded File:Nephrocalcinosis x-ray.png
- 09:31, 6 May 2022 Nikolas talk contribs created page File:Psammoma bodies.jpg
- 09:31, 6 May 2022 Nikolas talk contribs uploaded File:Psammoma bodies.jpg
- 09:30, 6 May 2022 Nikolas talk contribs created page 13. Endogenous non-hemoglobinogenic pigments. Lipofuscin, melanin, homogentizic acid (Created page with "We’ve seen the haemoglobinogenic pigments, now it’s time to discuss the other endogenous pigments: lipofuscin, melanin and homogentisate. == Lipofuscin == We’ve met with lipofuscin before; it’s presence in normal in aged heart, liver and brain cells is physiological. The insoluble brownish-yellow “wear and tear” pigment is not dangerous to the cell but is a sign of earlier free radical injury. The lipofuscin itself is a complex of lipids and proteins. The l...") Tag: Visual edit
- 09:29, 6 May 2022 Nikolas talk contribs created page File:Ochronosis.png
- 09:29, 6 May 2022 Nikolas talk contribs uploaded File:Ochronosis.png
- 09:29, 6 May 2022 Nikolas talk contribs created page 12. Hemoglobinogenic pigments II. Pathological forms of iron storage (Created page with "== Haemosiderin == The other haemoglobin-derived pigment is haemosiderin. It has a golden yellow-brownish colour and accumulates in tissues when there is a local or system excess of iron. Iron is usually stored in cells being bound to the protein apoferritin, together forming ferritin. Haemosiderin is comprised of denatured ferritin. While the iron inside ferritin can be used when the body needs it, the iron inside haemosiderin is lost, and cannot be used by the body an...") Tag: Visual edit
- 09:27, 6 May 2022 Nikolas talk contribs created page 11. Hemoglobinogenic pigments I. Causes and forms of jaundice (Created page with "== Bilirubin == Bilirubin is a breakdown product of the porphyrin rings of haemoglobin. Bilirubin is therefore a haemoglobinogenic pigment with a yellow-orange colour. It doesn’t contain iron. Bilirubin is insoluble in water and is therefore transported by albumin to the liver, where the hepatocytes conjugate it with glucuronic acid by biotransformation. After it becomes conjugated it becomes more water-soluble, so the liver therefore pours it into the bile. The bile...") Tag: Visual edit
- 09:27, 6 May 2022 Nikolas talk contribs created page File:Jaundice.jpg
- 09:27, 6 May 2022 Nikolas talk contribs uploaded File:Jaundice.jpg
- 09:25, 6 May 2022 Nikolas talk contribs created page 10. Histochemical characteristics of the different pigments. Exogenous pigments (Created page with "First of all, what is a pigment? A pigment is a colored substance that can be both exogenous or endogenous. Exogenous pigments come from the outside of the body, like carbon dust or a tattoo. Endogenous pigments are synthetized within the body and can be lipofuscin, melanin and derivatives of hemoglobin. Accumulation of these pigments is associated with dysfunction of the cell. == Endogenous pigments == === Histochemical characteristics === Let’s see how we can stain...") Tag: Visual edit
- 09:22, 6 May 2022 Nikolas talk contribs created page 9. Pathomorphology, pathogenesis and complications of atherosclerosis (Created page with "''Written by ms Worldwide, edited by Nikolas'' ''Atherosclerosis'' means “gruel hardening” and is one of the worst guys when it comes to increased morbidity and mortality in the Western world. It underlies the pathogenesis of coronary, cerebral and peripheral vascular disease. So, make sure to understand and learn this well, because this will follow you through your whole career as a medical doctor. Also, don’t mix arteriosclerosis and atherosclerosis. Thickening...") Tag: Visual edit
- 09:21, 6 May 2022 Nikolas talk contribs created page File:Pathomechanism of atherosclerosis.jpg
- 09:21, 6 May 2022 Nikolas talk contribs uploaded File:Pathomechanism of atherosclerosis.jpg
- 09:19, 6 May 2022 Nikolas talk contribs created page 8. The definition and types of degenerations. Parenchymal and fatty degeneration. Organ examples (Created page with "Degeneration is a form of deterioration. It can be explained as the change of a tissue to a lower or less functionally active form. Degeneration is sublethal injuries to the cells. It doesn’t kill the tissue, but the tissue will have some damages or flaws that can make it less functional. Many of them are related to aging and genetics and can get worse by a poor lifestyle and eating habits. There are many types of degeneration, and all of them are characterized by ac...") Tag: Visual edit
- 09:18, 6 May 2022 Nikolas talk contribs created page File:Parenchymal degeneration.png
- 09:18, 6 May 2022 Nikolas talk contribs uploaded File:Parenchymal degeneration.png
- 09:17, 6 May 2022 Nikolas talk contribs created page 7. Apoptosis morphology, pathomechanism (Created page with "In contrast to necrosis, apoptosis can be physiological. When cells are no longer needed, they are instructed to die by apoptosis, which doesn’t cause inflammation. The cell contents don’t burst into the surroundings but are instead packed into apoptotic bodies that are later removed by macrophages. Apoptosis is seen in many physiological situations. Some examples: * During development of your fingers and toes during embryogenesis, the cells between the fingers and...") Tag: Visual edit
- 09:15, 6 May 2022 Nikolas talk contribs created page 6. Caseous necrosis and adiponecrosis (Created page with "== Adiponecrosis == thumb|Fat necrosis in acute pancreatitis. The white chalky deposits are the saponificated remains of the fat in the mesentery and around the pancreas. Also called fat necrosis, adiponecrosis is a necrosis of adipose tissue, often caused by release of activated pancreatic lipases into the pancreas and peritoneal cavity. The lipases digest the cell membranes of adipocytes and then split the triacylglycerol...") Tag: Visual edit
- 09:15, 6 May 2022 Nikolas talk contribs created page File:Caseous necrosis in the lung..jpg
- 09:15, 6 May 2022 Nikolas talk contribs uploaded File:Caseous necrosis in the lung..jpg
- 09:15, 6 May 2022 Nikolas talk contribs created page File:Fat necrosis in acute pancreatitis.jpg
- 09:15, 6 May 2022 Nikolas talk contribs uploaded File:Fat necrosis in acute pancreatitis.jpg
- 09:14, 6 May 2022 Nikolas talk contribs created page 5. Patterns of liquefactive type necrosis. Organ examples (Created page with "In liquefactive necrosis the tissue is turned into a liquid mass, hence the name. Common for all types of liquefactive necrosis is that the cells are completely digested by enzymes, which results in a soft lesion consisting of fluid remains of necrotic tissue. We have two main types, encephalomalacia and abscess formation. == Encephalomalacia == thumb|Encephalomalacia of the brain Also called cerebral infarct, encephalomalacia...") Tag: Visual edit
- 09:14, 6 May 2022 Nikolas talk contribs created page File:Lung abscess.jpg
- 09:14, 6 May 2022 Nikolas talk contribs uploaded File:Lung abscess.jpg
- 09:13, 6 May 2022 Nikolas talk contribs created page File:Encephalomalacia of the brain.jpg
- 09:13, 6 May 2022 Nikolas talk contribs uploaded File:Encephalomalacia of the brain.jpg
- 09:13, 6 May 2022 Nikolas talk contribs created page 4. Patterns of coagulation type necrosis. Organ examples (Created page with "Necrosis (on the macroscopical level) can be divided into four types, coagulative type, liquefactive type, caseation type and adiponecrosis. In the coagulative type of necrosis, the rough tissue structure is upheld and can be recognized. Four subtypes of coagulative necrosis exist, infarct, decubitus, pseudomembrane formation and gangrene. == Infarct == An infarct is an area of ischemic necrosis in an organ that is caused by occlusion (blockage) of the supplying artery...") Tag: Visual edit