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- 10:30, 21 March 2023 Nikolas talk contribs created page 35. Pharmacology of eicosanoids. Drugs acting on smooth muscle (Created page with "== Eicosanoids == thumb|318x318px|Synthesis of eicosanoids. You already know these bad boys, prostaglandins, thromboxanes and leukotrienes. They’re synthesized from membrane phospholipids, which are first converted into arachidonic acid by ''phospholipase A2''. These molecules are very short-lived, meaning that they’re rapidly broken down in plasma after they’re produced. Their half-life is only 1 minute! They’re called eicosano...") Tag: Visual edit