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- 10:20, 6 May 2022 Nikolas talk contribs created page 21. Left ventricular hypertrophy. Causes, sequential compensatory changes and functional consequences (Created page with "Cardiac hypertrophy is an adaptive mechanism, so the heart can compensate for the increased afterload. However, after a certain limit the heart cannot compensate any longer, and regressive changes will happen instead, like lysis and loss of myocardial fibers. In extreme cases apoptosis or necrosis of myocytes will happen. All of this leads to a cardiac failure. The left ventricle can undergo both concentric and dilative hypertrophy. The way to measure the extent of the...") Tag: Visual edit