34. Seminoma: Difference between revisions
(Created page with "'''Staining''': HE '''Organ''': Testis '''Description''': As with any seminoma is germ cell neoplasia in situ (GCNIS) present. There are two smaller tumor foci and one that is larger. The larger tumor focus is divided by eosinophilic septa, which is responsible for the lobulated macroscopical morphology. The tumor cells are large, show severe atypia and have very bright cytoplasm due to their high glycogen content. The tumor cells are separated by a lymphocytic strom...") |
(No difference)
|
Revision as of 19:12, 15 November 2022
Staining: HE
Organ: Testis
Description:
As with any seminoma is germ cell neoplasia in situ (GCNIS) present. There are two smaller tumor foci and one that is larger. The larger tumor focus is divided by eosinophilic septa, which is responsible for the lobulated macroscopical morphology.
The tumor cells are large, show severe atypia and have very bright cytoplasm due to their high glycogen content. The tumor cells are separated by a lymphocytic stroma.
Diagnosis: Seminoma
Causes:
- 30 – 40 year old males
Theory:
Seminomas never contain necrosis. The high glycogen content of the tumor cells make them PAS positive. The conventional (clear cell) renal cell carcinoma has similar-looking cytoplasm, but those tumor cells wouldn’t be PAS positive.
