41. Arteritis temporalis: Difference between revisions
(Created page with "'''Staining''': HE '''Organ''': Superficial temporal artery '''Description''': Three cross-sections of an artery can be seen. The upper right one is the easiest to examine. We can see giant cells, epithelioid cells, lymphocytes and plasma cells. The lumen of the artery is really narrow and the internal elastic lamina is disrupted. '''Diagnosis''': Temporal arteritis, a form of giant cell arteritis '''Etiology''': * Older people * Females more affected than males '...") |
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'''Staining''': HE | [[File:Temporal arteritis overview.png|thumb|Overview of the slide]]'''Staining''': HE | ||
'''Organ''': Superficial temporal artery | '''Organ''': Superficial temporal artery | ||
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* Females more affected than males | * Females more affected than males | ||
'''Theory''': | '''Theory''':[[File:Temporal arteritis disruption of the IEM.png|thumb|Close-up of the upper right section. The dark purplish lining that looks irregular shows the disruption of the internal elastic lamina.]]Giant cell arteritis, or temporal arteritis (when it affects the temporal artery) is a granulomatous inflammation that affects large arteries. Characteristic for the disease is that only certain parts of the affected artery show the histological signs of inflammation. If a preparation was taken from one of these parts could a false negative diagnosis be made. Optimally should a longitudinal section of the artery be examined, or multiple cross-sections (which could be why we have three sections here). | ||
[[File:Temporal arteritis giant cells.png|thumb|From the upper right section. The cells with small cytoplasm and dark nuclei are lymphocytes and plasma cells|left]] | |||
Giant cell arteritis, or temporal arteritis (when it affects the temporal artery) is a granulomatous inflammation that affects large arteries. Characteristic for the disease is that only certain parts of the affected artery show the histological signs of inflammation. If a preparation was taken from one of these parts could a false negative diagnosis be made. Optimally should a longitudinal section of the artery be examined, or multiple cross-sections (which could be why we have three sections here). | [[File:Temporal arteritis IEM.png|thumb|Also from the upper right section.]] | ||
[[File:Temporal arteritis giant cells.png | |||
[[File:Temporal arteritis IEM.png | |||
[[Category:Pathology 1 - Histopathology slides]] | [[Category:Pathology 1 - Histopathology slides]] | ||
Revision as of 12:27, 5 July 2024
Staining: HE
Organ: Superficial temporal artery
Description:
Three cross-sections of an artery can be seen. The upper right one is the easiest to examine. We can see giant cells, epithelioid cells, lymphocytes and plasma cells. The lumen of the artery is really narrow and the internal elastic lamina is disrupted.
Diagnosis: Temporal arteritis, a form of giant cell arteritis
Etiology:
- Older people
- Females more affected than males
Theory:
Giant cell arteritis, or temporal arteritis (when it affects the temporal artery) is a granulomatous inflammation that affects large arteries. Characteristic for the disease is that only certain parts of the affected artery show the histological signs of inflammation. If a preparation was taken from one of these parts could a false negative diagnosis be made. Optimally should a longitudinal section of the artery be examined, or multiple cross-sections (which could be why we have three sections here).
