33. Squamous metaplasia in bronchus: Difference between revisions

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(Created page with "'''Staining''': HE '''Organ''': Bronchi, lymph node '''Description''': We can see two cuts of a bronchus and two pieces of a lymph node. The top bronchus is the best, so we’ll use that. Cartilage and submucosal glands are present. In a small part of the bronchus is the epithelium stratified squamous. The lymph nodes show anthracosis. '''Diagnosis''': Squamous metaplasia in bronchus '''Causes''': * Smoking '''Theory''': Cartilage and submucosal glands show us...")
 
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'''Staining''': HE
[[File:Squamous metaplasia in bronchus overview.jpg|thumb|Overview. The top bronchus is the best, so we’ll use mainly that.]]'''Staining''': HE


'''Organ''': Bronchi, lymph node
'''Organ''': Bronchi, lymph node
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This type of metaplasia is characteristic in smokers and is a precancerous or preneoplastic lesion toward lung cancer.
This type of metaplasia is characteristic in smokers and is a precancerous or preneoplastic lesion toward lung cancer.
[[File:Squamous metaplasia in bronchus overview.jpg|center|thumb|Overview. The top bronchus is the best, so we’ll use mainly that.]]
[[File:Squamous metaplasia in bronchus anthracosis.jpg|thumb|Anthracosis in the lymph node|left]]
[[File:Squamous metaplasia in bronchus anthracosis.jpg|center|thumb|Anthracosis in the lymph node]]
[[File:Squamous metaplasia in bronchus normal epithelium.png|thumb|Normal respiratory epithelium – pseudostratified kinociliated columnar epithelium.]]
[[File:Squamous metaplasia in bronchus normal epithelium.png|center|thumb|Normal respiratory epithelium – pseudostratified kinociliated columnar epithelium.]]
[[File:Squamous metaplasia in bronchus bronchus.png|thumb|Close up of the top bronchus. Metaplasia has only occurred in a small part of the epithelium. Submucosal glands can also be seen.|left]]
[[File:Squamous metaplasia in bronchus bronchus.png|center|thumb|Close up of the top bronchus. Metaplasia has only occurred in a small part of the epithelium. Submucosal glands can also be seen.]]
[[File:Squamous metaplasia in bronchus metaplasia.png|thumb|The epithelium here is clearly not respiratory epithelium anymore, but stratified squamous epithelium instead]]
[[File:Squamous metaplasia in bronchus metaplasia.png|center|thumb|The epithelium here is clearly not respiratory epithelium anymore, but stratified squamous epithelium instead]]
[[Category:Pathology 1 - Histopathology slides]]
[[Category:Pathology 1 - Histopathology slides]]

Latest revision as of 12:06, 5 July 2024

Overview. The top bronchus is the best, so we’ll use mainly that.

Staining: HE

Organ: Bronchi, lymph node

Description:

We can see two cuts of a bronchus and two pieces of a lymph node.

The top bronchus is the best, so we’ll use that. Cartilage and submucosal glands are present. In a small part of the bronchus is the epithelium stratified squamous.

The lymph nodes show anthracosis.

Diagnosis: Squamous metaplasia in bronchus

Causes:

  • Smoking

Theory:

Cartilage and submucosal glands show us that we’re looking at a bronchus and not a bronchiolus.

Most of the epithelial is healthy, respiratory epithelium with goblet cells. Only a small part of the epithelium shows stratified non-keratinizing squamous epithelial metaplasia.

This type of metaplasia is characteristic in smokers and is a precancerous or preneoplastic lesion toward lung cancer.

Anthracosis in the lymph node
Normal respiratory epithelium – pseudostratified kinociliated columnar epithelium.
Close up of the top bronchus. Metaplasia has only occurred in a small part of the epithelium. Submucosal glands can also be seen.
The epithelium here is clearly not respiratory epithelium anymore, but stratified squamous epithelium instead