Squamous cell carcinoma of the skin: Difference between revisions
(Created page with "<section begin="dermatology" /> * Second most common skin cancer * Risk factors ** Chronic sun exposure ** Precancerous lesions *** Actinic keratosis *** Bowen disease (SCC in situ) *** Leukoplakia ** Radiation ** Chronic scars, ulcers ** Arsenic, tar * Clinical features ** Painless, non-healing, bleeding ulcer or nodule ** Rapid growing ** On sun-exposed areas *** Face and neck *** Lower lip * Prognosis ** 5% risk of metastasis * Diagnosis ** Punch biopsy * Treatment **...") |
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Revision as of 11:44, 18 June 2024
- Second most common skin cancer
- Risk factors
- Chronic sun exposure
- Precancerous lesions
- Actinic keratosis
- Bowen disease (SCC in situ)
- Leukoplakia
- Radiation
- Chronic scars, ulcers
- Arsenic, tar
- Clinical features
- Painless, non-healing, bleeding ulcer or nodule
- Rapid growing
- On sun-exposed areas
- Face and neck
- Lower lip
- Prognosis
- 5% risk of metastasis
- Diagnosis
- Punch biopsy
- Treatment
- Surgical excision with 5 mm safety border
- Radiation therapy
- Mohs micrographic surgery
- For low-risk, small
- Cryotherapy
- Curettage
- For metastasis
- Chemotherapy
- Platina
- 5-FU
- EGFR inhibitors – cetuximab
- PD-1 inhibitor – cemeplimab
- Chemotherapy
- Follow-up
- Physical examination
- Regional ultrasound
- Chest x-ray
- Abdominal US
- Sun protection