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'''Hyperparathyroidism''' refers to the increased activity of the parathyroid glands, causing elevated levels of [[PTH]]. We distinguish primary, secondary, and tertiary hyperparathyroidism. | '''Hyperparathyroidism''' refers to the increased activity of the parathyroid glands, causing elevated levels of [[PTH]]. We distinguish primary, secondary, and tertiary hyperparathyroidism. | ||
Primary hyperparathyroidism is caused by local parathyroid pathology, which is the most important cause. Secondary hyperparathyroidism occurs as a response to [[hypocalcaemia]], causing the parathyroid glands to overproduce PTH. Tertiary hyperparathyroidism occurs due to long-standing secondary hyperparathyroidism, in which the parathyroid glands have been overstimulated for so long that they continue to overproduce PTH even if the original stimulus is removed. | Primary hyperparathyroidism is caused by local parathyroid pathology, which is the most important cause of hyperparathyroidism overall. Secondary hyperparathyroidism occurs as a response to [[hypocalcaemia]], causing the parathyroid glands to overproduce PTH. Tertiary hyperparathyroidism occurs due to long-standing secondary hyperparathyroidism, in which the parathyroid glands have been overstimulated for so long that they continue to overproduce PTH even if the original stimulus is removed. | ||
== Etiology == | == Etiology == | ||
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Management for secondary hyperparathyroidism involves treating the underlying cause. Dietary restriction of phosphate and [[Vitamin D supplement|vitamin D supplements]] are also important. [[Phosphate binder|Phosphate binders]] may be used in case hyperphosphataemia remains despite dietary restriction. Cinacalcet may also be used. | Management for secondary hyperparathyroidism involves treating the underlying cause. Dietary restriction of phosphate and [[Vitamin D supplement|vitamin D supplements]] are also important. [[Phosphate binder|Phosphate binders]] may be used in case hyperphosphataemia remains despite dietary restriction. Cinacalcet may also be used. | ||
<noinclude>[[Category:Endocrinology]] | <noinclude>[[Category:Endocrinology]] | ||
[[Category:Endocrine surgery]]</noinclude> | [[Category:Endocrine surgery]] | ||
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