Nikolas
Created page with "<section begin="clinical biochemistry" />'''Uric acid''' (or '''urate''') is a metabolic breakdown product of purines. Purines are metabolised to xanthine and then to uric acid by xanthine oxidase. Deposition of uric acid crystals in joints is the driving mechanism in attacks of gout. Deposition of uric acid crystals in the kidney can cause uric acid nephropathy. Elevated uric acid is seen in gout, but is also seen in tumour lysis syndrome, ..."