Nikolas
Created page with "== Summary == * Certain drugs are bound to proteins in the plasma, mostly albumin * Drugs that have extensive plasma protein binding have: ** Delayed onset of effect ** Longer duration * Volume of distribution (Vd) illustrates where in the body the drug is distributed (i.e. only in plasma, in plasma and interstitium, plasma + interstitium + intracellular or inside tissues) ** The higher the Vd value for the drug, the more fluid spaces the drug distributes itself into **..."