Pemphigus vulgaris: Revision history

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17 July 2024

  • curprev 17:5117:51, 17 July 2024‎ Nikolas talk contribs‎ 717 bytes +717‎ Created page with "<section begin="dermatology" />* In middle-aged, elderly * Deadly without treatment * Pathomechanism ** Autoantibodies against desmosomes ** Acantholysis – loss of cell-cell adhesion * Clinical features ** Painful, flaccid, intraepidermal (superficial) blisters ** -> lesions rupture ** -> erosions and crusts ** -> re-epithelialization with hyperpigmentation but no scarring ** No pruritus ** Lesions often begin in oral mucosa then to body parts exposed to pressure * Dia..." Tag: Visual edit