8. Biotransformation of drugs: Revision history

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16 March 2023

  • curprev 13:1313:13, 16 March 2023‎ Nikolas talk contribs‎ 16,352 bytes +16,352‎ Created page with "== Summary == * The body metabolizes drugs in two steps; phase I and phase II * Phase I, where the drug is oxidized, reduced or hydrolysed to yield an -OH group ** The most important enzymes in phase I reactions are the CYP450 enzymes, monoamine oxidase, alcohol dehydrogenase, etc * Phase II, where the enzyme attaches a chemical group to the -OH group on the drug ** The important enzymes here are ''transferases'', enzymes which conjugate the drug with a chemical group *..." Tag: Visual edit