76. Antifungal drugs: Revision history

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26 April 2023

  • curprev 13:3713:37, 26 April 2023‎ Nikolas talk contribs‎ 5,717 bytes +5,717‎ Created page with "== Polyenes == === Compounds === * Amphotericin B * Nystatin * Natamycin === Indications === Amphotericin is the first choice for severe systemic fungal infections. Nystatin and natamycin are too toxic for systemic use and instead used topically for oral and vaginal candidiasis. === Mechanism of action === Polyenes disrubt fungal cell wall synthesis by binding to ergosterol in the fungal cell membrane, which leads to formation of pores in the membrane, causing leaka..." Tag: Visual edit